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FIRST EVIDENCE FOR AN ‘ENVIRONMENTAL’ miR PROFILE FOR SPORADIC ALZHEIMER’S DISEASE

Skrevet af ToxGenSolutions BV d. . Uploaded i Breaking News.

After several months of lockdown, the Interreg. VL-NL supported project Herinneringen (Memories) was able to finalize the genetic analyses of the human iPSC derived neurons exposed to selected environmental risk factors and biopsies from Alzheimer’s patients and control individuals. Differential gene and pathway analysis revealed processes in patient derived iPSC and biopsies that were not seen in material from control individuals. Currently, 9 miR’s have caught our attention for further evaluation.

  • Ackowledgements
    Acknowledgements

ToxGenSolutions BV

Erwin L Roggen (CEO): More than 25 years of industrial experience (including 15 years as a manager) in the development, implementation and use of animal-free methods; Self-employed since 2013 (www.3rsmc-aps.com) with the mission to valorise promising animal-free methods; Founder and co-owner (2011) of the listed company SenzaGen AB (Lund, Sweden) (www.senzagen.com), specialized in cell-based identification methods for allergens. profile: http://www.linkedin.com/profile/view?id=23021602&trk=tab_pro

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